CURRENT VIEWS ON TOXIC HEPATITIS DRUG-INDUCED

Abstract

Damage to the liver caused by drugs or non-drug substances is called hepatotoxicity. The risk of developing hepatotoxicity is due to several factors, including individual intolerance, gender, alcohol consumption of smoking concomitant other medications, presence of liver disease, and genetic and environmental characteristics [4]. Although most lipophilic drugs are capable of causing liver damage, antibiotics nonsteroidal anti-inflammatory drugs (NSAIDs), and anticonvulsants stand out as the most frequent provocateurs of hepatotoxicity. Intravenously administered drugs, such as antibiotics and tumour drugs, also show the strongest association with hepatic toxicity.