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Please use this identifier to cite or link to this item: http://repo.tma.uz/xmlui/handle/1/1788
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dc.contributor.authorAkramova N.T., Nabiyeva D. A., Bobomurodov T.A., Bobomurodova D.T.-
dc.date.accessioned2025-06-05T12:57:07Z-
dc.date.available2025-06-05T12:57:07Z-
dc.date.issued2025-
dc.identifier.urihttp://repo.tma.uz/xmlui/handle/1/1788-
dc.description.abstractMaqsad: podagra bilan og’rigan bemorlarda MTH FR C677T (A223V), PAI-1 675 4G/5G polimorfizmlarini aniqlash. Material va usullar: podagra bilan og’rigan 98 bemor tekshirildi. Venoz qondagi yadroli hujayralar massasi eritrotsitlarni 5,0 ml li probirkalarda maxsus fiziologik eritma (NH4 Cl, KHCO3 va EDTA) bilan qonga nis bati 1: 3 bo’lgan eritrotsitlar lizisi bilan ajratilgan. Xona haroratida 10 daqiqa davomida inkubatsiya qilingandan so’ng, naychalar 5 daqiqa davomida 3000 rpm tezlikda sentrifugalanadi. Natijalar: MTHFR C677T (A223V) va PAI-1 675 4G/5G gen polimorfizmlarini o’rganish shuni ko’rsatdiki, ko’pchilik bemorlarda tromboz va yurak-qon tomir kasalliklari xavfini oshirishi mumkin bo’lgan gene tik o’zgarishlar mavjud. Xulosa: podagra bilan og’rigan bemorlarda gemostazning genetik tahlili zarur.en_US
dc.language.isootheren_US
dc.publisherO'zbekiston, Toshkenten_US
dc.relation.ispartofseriesUDK;616.72-002:616.13-005.3:575.113-
dc.subjectpodagra, gemostaz, molekulyar-genetik polimorfizm, MTHFR C677T, PAI-1 675 4G/5G, giperurike miya, tromboz, yurak-qon tomir kasalliklari.en_US
dc.titlePODAGRA BILAN HASTALANGAN BEMORLARDA GEMOSTAZ TIZIMIDAGI MOLEKULYAR GENETIK POLIMORFIZMLARen_US
dc.typeArticleen_US
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