PNPLA3 GENE POLYMORPHISM AS A GENETIC MARKER OF BONE MINERAL DENSITY DISORDERS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE

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Title:	PNPLA3 GENE POLYMORPHISM AS A GENETIC MARKER OF BONE MINERAL DENSITY DISORDERS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
Authors:	Karimov M.M Zufarov P.S Sobirova G.N Aripdzhanova Sh.S Avazova G.N
Keywords:	nonalcoholic fatty liver disease, PNPLA3 gene, osteoporosis
Issue Date:	2025
Publisher:	НАУЧНАЯ И ИННОВАЦИОННАЯ ТЕРАПИЯ Научный журнал по научной и инновационной терапии основано в 2022 году Бухарским государственным медицинским институтом имени Абу Али ибн Сино
Abstract:	The results of investigation of bone mineral density of 100 patients with nonalcoholic fatty liver disease (NAFLD) were presented in the article. Studies included a definition of biochemical markers of bone metabolism and ultrasonic densitomety of bone density. Significantly increasing of bone resorption of of bcross laps indicator and reduction of densitometric parameters T and Z - criteria in patients with NAFLD and pathological G allele of PNPLA 3 (rs738409) were revealed.
URI:	http://repo.tma.uz/xmlui/handle/1/2556
ISSN:	2181-418X
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