Elimination of the Wound Defect in Experimental Diabetic Foot Syndrome Using Collagen in Composite Form

Abstract

At the same time, worldwide, diabetes mellitus remains a widespread, urgent disease with frequent comorbidities, frequent complications, and unresolved problems. Globally, currently, 537 million out of every 10 adults aged 20 to 79 are diagnosed with DM. According to the International Diabetic Federation, the incidence of DM among the adult population will reach 552 million people by 2030. The effectiveness and significance of bioplastic collagen preparations in the treatment of acute and chronic ulcers have been undeniably confirmed in the literature. Medical preparations based on collagen have already been introduced into practice, and the pathophysiological and surgical study of the effective stimulation of the regenerative and proliferative periods in the wound healing stage will give impetus to the experimental use of composite collagen in DFS. Based on this, an experimental study was conducted on the short-term healing of wound defects with the experimental use of composite collagen in DFS.