Pathomorphology of Mesenteric Lymph Nodes in Infants Who Died from Peritonitis in the Neonatal Period

Abstract

Peritonitis in infants in the neonatal period, mainly primary hematogenous, lymphogenous foci, necrotic enterocolitis, is a process that occurs in the perforation of the intestines, and as a result of sepsis, septicopyemia, purulent inflammation of all layers of the peritoneum, in addition to massive atrophic, sclerotic changes in the regional lymph nodes, acute insufficiency of all morphofunctional layers, leading to T and B cell collapse, delymphatization in the lymph node and lymph node reticulocytosis. It was found that in the subcapsular and medullary layers of the lymph node, coarsely dispersed proteinaceous deposits consisting of various damaged tissue and cell components were accumulated.