Comparative Assessment of Intestinal Dysbacteriosis During Pregnancy With Pathology

Abstract

Recent research has shown a significant increase in interest surrounding the study of intestinal microflora, with advancements in molecular genetic diagnostic methods. Studies indicate that pregnancy brings considerable changes to the intestinal microbiota, which are critical for maintaining a healthy gestational period. However, certain factors, both endogenous and exogenous, may disrupt this balance, potentially leading to complications such as preeclampsia, spontaneous abortion, or premature birth. This study aimed to evaluate the composition of intestinal microflora in 200 pregnant women using real-time PCR. The results revealed intestinal dysbiosis in all subjects, with varying degrees of severity. The findings also indicated a correlation between the severity of dysbiosis and gastrointestinal history, as well as vaginal dysbiosis, suggesting a strong link between the two biotopes.