Impared endothelial dysfunction in patients with ankylosing spondylitis

Abstract

80 patients diagnosed with ankylos- ing spondylitis were examined and were treated at the rheu- matology department of the Tashkent Clinical Hospital: Group 1 - 40 patients with ankylosing spondylitis without a post- COVID period, Group 2 - 40 patients with ankylosing spon- dylitis and a post-COVID period. The control group consisted of 40 healthy people without a history of acute and chronic diseases. Results: A study of the functional state of the endo- thelium with a reactive hyperemia test showed a decrease in the diameter of the brachial artery from the expected value 60 and 120 seconds after decompression, as well as an increase in maximum systolic and a decrease in maximum diastolic blood flow in the main group. Conclusions: The results of the exam- ination indicate a violation of the resistance of the vascular wall against the background of endothelial dysfunction.