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http://repo.tma.uz/xmlui/handle/1/367| Title: | Genetic polymorphism of gene ptpn22 in autoimmune diseases |
| Authors: | Rakhimova M.B., Akhmedov Kh.S. |
| Keywords: | PTPN22, single nucleotide polymorphisms, autoimmune diseases, genetic association. |
| Issue Date: | 2024 |
| Citation: | Toshkent |
| Series/Report no.: | UDC;616.72-002.772 |
| Abstract: | In this review, we summarize the mechanism of how PTPN22 and its genetic variants are involved in the patho- physiology of autoimmune diseases. In addition, we sum up the findings of studies reporting the genetic association of PTPN22 with different types of diseases, including type 1 diabetes mellitus, systemic lupus erythematosus, juvenile idiopathic arthritis, and several other diseases. By understanding these findings comprehensively, we can explain the complex etiology of autoimmunity and help to determine the criteria of disease diagnosis and prognosis, as well as medication developments. |
| URI: | http://repo.tma.uz/xmlui/handle/1/367 |
| ISSN: | 2181-7812 |
| Appears in Collections: | Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Akhmedov Kh.S. Rakhimova M.B., (2).pdf | Genetic polymorphism of gene ptpn22 in autoimmune diseases | 17.93 MB | Adobe PDF | View/Open |
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