Please use this identifier to cite or link to this item: http://repo.tma.uz/xmlui/handle/1/3891
Title: DYNAMICS OF IMMUNO-RHEUMATOLOGICAL PARAMETERS IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS DURING PREGNANCY
Authors: Akhrorov Abdulaziz Azizjonovich, Toshpulatov Sardorjon Sarvarjonovich, Mamasiddikova Sevinch Bakhadirovna, Mamasiddikova Akmaljon Anvarjonovich, Urokova Zarinabonu Ulugbekovna, Shomukhiddinov Shorasul Shomakhmudovich, Sharopova Aysulu Tursinbekovna
Keywords: systemic lupus erythematosus (SLE), pregnancy, immuno-markers, antinuclear antibodies (ANA), anti-dsDNA, complement C3/C4, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR)
Issue Date: 2026
Publisher: O'zbekiston, Toshkent (Tibbiyot asoslari xalqaro jurnali) N10
Series/Report no.: UDC;616.5-002.525:618.3
Abstract: In pregnant women with systemic lupus erythematosus (SLE), immuno-rheumatological parameters—including antinuclear antibodies (ANA), anti-double-stranded DNA antibodies (anti-dsDNA), complement components C3 and C4, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR)—demonstrate significant changes across each trimester of pregnancy. This article analyzes the dynamics of these biomarkers over the past five years of scientific research, their association with SLE disease activity, and their impact on pregnancy outcomes. These biomarkers play an important role in predicting maternal immune response and SLE activity and are essential for clinical monitoring
URI: http://repo.tma.uz/xmlui/handle/1/3891
ISSN: 3060-494X
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