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http://repo.tma.uz/xmlui/handle/1/4162| Title: | THE ROLE OF ANGIOTENSINOGEN (AGT) IN ATHEROSCLEROTIC RENAL ARTERY DISEASE |
| Authors: | Nazarova N.O |
| Keywords: | chronic kidney disease, renal artery atherosclerosis, urea, creatinine, cystatin C, endothelin1, proteinuria |
| Issue Date: | 2026 |
| Publisher: | O'zbekiston, Toshkent ( O‘ZBEKISTON TIBBIYOT AXBOROTNOMASI JURNALI ) |
| Abstract: | Atherosclerotic renal artery disease (ARAD) is a major cause of secondary hypertension and ischemic nephropathy. Angiotensinogen (AGT), as the precursor of angiotensin peptides in the renin-angiotensin-aldosterone system (RAAS), is central to many of the pathophysiologic mechanisms in ARAD. In this review, we examine clinical studies on AGT gene polymorphisms, outcomes of RAAS blockade, and the impact of AGT-fo cused therapies in ARAD. The aim is to clarify what is known, what remains controversial, and which areas merit further investigation |
| URI: | http://repo.tma.uz/xmlui/handle/1/4162 |
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Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 10_THE_ROLE_OF_ANGIOTENSINOGEN_AGT_IN_ATHEROSCLEROTIC_RENAL_ARTERY.pdf | 2.14 MB | Adobe PDF | View/Open |
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