THE ROLE OF APOLIPOPROTEIN E IN ATHEROSCLEROTIC RENAL ARTERY DISEASE

Abstract

Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide, with atherosclerosis being a major underlying pathology. Among the various manifestations of atherosclerosis, atherosclerotic renal artery disease (ARAD) is of particular clinical importance due to its association with renovascular hypertension, chronic kidney disease (CKD), and an increased risk of cardiovascular events. Despite advancements in diagnostic and therapeutic approaches, ARAD often progresses silently and is frequently diagnosed at advanced stages, making early identification of risk factors crucial.