Hormonal Imbalance in a Patient with Bronchial Asthma: Key Aspects

Abstract

Chronic inflammation contributes to the remodeling of the repiratory tract, resulting in irreversible structural alterations and a progressive decline in pulmonary function. These pathological changes inevitably compromise the quality of life in pediatric patients, heightening the risk of early disability and adversely influencing their psychoemotional well-being. Morever, bronchial obstruction and hypoxic states in individuals with bronchial asthmaprofoundly impact the regulation of hormonal mechanisms within the reproductive system. Objective. The patient with bronchial asthma with the hormonal balance features. Materials and methods. 16-year-old patient case report, which is including the anamnesis vitae, anamnesis morbi, family anamnesis according to the disease, complaints, objective and physical methods of investigation, laboratory analysis CBT, hormones analysis by CLIA method, instrumental methods to establish the stages of BA. Results and discussion. Based on patient’s hormonal profile, elevated levels of prolactin and testosterone were identified, suggesting that stress-induced adaptive mechanisms, along with hormone therapy administered due to the chronic hypoxic state, inevitably influenced the pituitary function within endocrine system. Conclusion. Sex hormones play a crucial role in pathogenesis and progressin of bronchial asthma. Estrogens contribute to heightened bronchial hyperreactivity, whereas testosterone, in contrast, exhibits protective effects