COMPLICATIONS IN RHEUMATOID ARTHRITIS PATIENTS  FOLLOWING KNEE JOINT REPLACEMENT: FINDINGS FROM A 26- WEEK PROSPECTIVE REAL-WORLD COHORT STUDY

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Title:	COMPLICATIONS IN RHEUMATOID ARTHRITIS PATIENTS FOLLOWING KNEE JOINT REPLACEMENT: FINDINGS FROM A 26- WEEK PROSPECTIVE REAL-WORLD COHORT STUDY
Authors:	Maruf Anorboev., Khalmurad Akhmedov., Ilkhom Khujanazarov
Issue Date:	18-Oct-2025
Publisher:	O'zbekiston, Termiz “FARMAKOLOGIYA, FARMATSEVTIKA VA XALQ TABOBATI: DOLZARB MUAMMOLAR VA INNOVATSIYALAR” MAVZUSIDAGI XALQARO ILMIY-AMALIY KONFERENSIYASI MATERIALLARI TO'PLAMI
Abstract:	Background: Reactive Arthritis (ReA) is an immune-mediated form of spondyloarthritis, often triggered by genitourinary or gastrointestinal infections. Current therapeutic strategies rely mainly on NSAIDs and cs-DMARDs, with biologics reserved for refractory disease. However, limited progress has been made in exploring novel targeted agents. Iguratimod 25 mg, an oral immunomodulatory drug approved for rheumatoid arthritis in Asia, has demonstrated anti-inflammatory and cytokine-suppressive properties, but evidence in ReA is scarce. Objectives: To evaluate the clinical efficacy and cytokine-modulating effects of Iguratimod 25 mg in patients with Reactive Arthritis compared to conventional and biologic therapy.
URI:	http://repo.tma.uz/xmlui/handle/1/4355
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