PATHOGENETIC MECHANISMS LINKING GASTROESOPHAGEAL REFLUX DISEASE WITH RESPIRATORY DISEASES

Please use this identifier to cite or link to this item: http://repo.tma.uz/xmlui/handle/1/4510

Title:	PATHOGENETIC MECHANISMS LINKING GASTROESOPHAGEAL REFLUX DISEASE WITH RESPIRATORY DISEASES
Authors:	Raimkulova N.R., Subkhanova Z.S
Keywords:	GERD, asthma, COPD, pathogenetic mechanisms, aspiration, vagal reflex, inflammation, impedance-pH monitoring.
Issue Date:	2024
Publisher:	O'zbekiston, Toshkent (YEVROSIYO PEDIATRIYA AXBOROTNOMASI) TIBBIY ILMIY- INNOVATSION JURNAL №2(20)
Abstract:	To study the pathogenetic mechanisms and clinical manifestations of GERD in asthma and COPD. Methods: A study of 68 patients with GERD, asthma, and COPD; diagnostics included impedance-pH monitoring, spirometry, and analysis of inflammatory markers (CRP, IL-6, IL-8). Results: Aspiration was more frequent in COPD (60%) and asthma (42%) patients. Elevated CRP, IL-6, IL-8 levels and vagal reflex hyperactivity were associated with bronchospasms. Conclusions: GERD exacerbates respiratory symptoms, requiring a comprehensive treatment approach.
URI:	http://repo.tma.uz/xmlui/handle/1/4510
Appears in Collections:

Files in This Item:

File	Description	Size	Format
ст.PATHOGENETIC MECHANISMS LINKING GASTROESOPHAGEAL REFLUX.pdf		554.83 kB	Adobe PDF	View/Open

DSpace JSPUI