SYMPTOMATIC SEIZURE IRON METABOLISM IN PATHOGENESIS AND FERROPOTASSIUM PROCESSES ROLE ANALYSIS TO DO

Abstract

This scientific in the article symptomatic seizure with sick iron metabolism in patients and ferropotassium processes pathogenetic importance The study involved 100 people. patient and 25 people healthy person attraction iron metabolism (iron, ferritin, transferrin) and ferropotassium marker 4 hydroxynonenal (4-HNE) levels as studied. 4-HNE level ELISA method using It was also determined that the patients clinical UPDRS status scale based on, neurostructural changes and through MRI evaluated. Results symptomatic in a fit of iron cell inside excess accumulation of ferritin increase and transferrin decrease with together, 4-HNE level sharp increased These cases ferropotassium activated and lipids peroxidation that it has increased MRI results indicate neurodegeneration that it has increased confirmed, UPDRS scores and clinical of symptoms weight reflection This indicators symptomatic of the seizure pathogenesis deep to understand, early diagnosis to put and individual therapy strategies working to go out opportunity creates. In particular, the level of 4-HNE clinical in practice as an effective biomarker recommendation to be possible.