| DC Field | Value | Language |
|---|
| dc.contributor.author | Durdona Saipova | - |
| dc.date.accessioned | 2026-09-08T09:53:21Z | - |
| dc.date.available | 2026-09-08T09:53:21Z | - |
| dc.date.issued | 2025-12-26 | - |
| dc.identifier.uri | http://repo.tma.uz/xmlui/handle/1/5119 | - |
| dc.description.abstract | Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and systemic inflammation. Growing evidence suggests a link between gut
microbiota alterations and metabolic dysregulation in COPD.
Methods: A cross-sectional study included 20 COPD patients (mean age: 65.4 ± 8.3 years,
57% male). Pulmonary function was assessed using FEV₁, FEV₁/FVC, and residual volume. Gut microbiota composition was analyzed via 16S rRNA sequencing, and plasma citrulline
and glycine levels were measured using LC-MS. Correlation analysis examined associations
between lung function, microbiota composition, and amino acid metabolism. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | European Respiratory Journal | en_US |
| dc.subject | COPD Gut microbiota Amino acid metabolism | en_US |
| dc.title | Association of Pulmonary Function, Gut Microbiota, and Amino Acid Metabolism in COPD Patients. | en_US |
| dc.type | Article | en_US |
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