MODERN VIEWS ON THE PROBLEM OF AMIODARONE-INDUCED THYROID DYSFUNCTION

Abstract

This review presents various perspectives of scientists regarding the effectiveness of Amiodarone as a preferred antiarrhythmic drug commonly used for the treatment of ventricular arrhythmias and atrial fibrillation (AF). However, due to the high toxicity of Amiodarone, there is a risk of potential damage to various organs, including the liver, lungs, cornea, skin, and thyroid gland. According to the scientific literature, the most commonly observed disorders associated with Amiodarone use are subclinical hypothyroidism (18%) and overt thyrotoxicosis (15.8%), with less frequent occurrences of overt hypothyroidism (1.5%) and subclinical thyrotoxicosis (1.5%). Continuous research in this field has led to a change in the understanding of the problem and the development of new approaches to the diagnosis and treatment of these disorders