Microbial Landscape in the Stomach of Patients with Urogenic Reactive Arthritis: A Study

Abstract

Abstract This study focuses on the impact of traditional pharmacotherapy on gastric microbiocenosis in patients with reactive arthritis (ReA) of urogenic origin. The research involved 27 patients, analyzing changes in the parietal and luminal microflora before and after treatment. The results revealed notable dysbiotic shifts, with peptostreptococci being the most frequently isolated microorganism, while staphylococci and micrococci declined post-treatment. The findings suggest that pharmacotherapy affects the balance of stomach microflora, reducing pathogenic bacteria and increasing opportunistic microbes. These shifts were also linked to the activity level of ReA. The study highlights the need for gastrointestinal health monitoring during ReA treatment to manage potential dysbiosis effectively. Future studies should explore the long­ term impacts of treatment and optimal methods for preserving healthy gastric microflora.