Abstract:
Damage to the liver caused by drugs or non-drug substances is called
hepatotoxicity. The risk of developing hepatotoxicity is due to several factors, including
individual intolerance, gender, alcohol consumption of smoking concomitant other
medications, presence of liver disease, and genetic and environmental characteristics [4].
Although most lipophilic drugs are capable of causing liver damage, antibiotics
nonsteroidal anti-inflammatory drugs (NSAIDs), and anticonvulsants stand out as the
most frequent provocateurs of hepatotoxicity. Intravenously administered drugs, such
as antibiotics and tumour drugs, also show the strongest association with hepatic
toxicity.
