Abstract:
When studying the immunohistochemical aspects of various clinical and morphological
types of atresia, which is one of the developmental anomalies of the esophagus, the
Chromogranin marker is used to identify secretory neurons that mark the neuromuscular
synapses of neuroendocrine cells and to determine whether the synthesis of functional peptide
bonds occurs. By its nature it is a glycoprotein marker, which makes it possible to assess the
morphofunctional state by staining the vesicles of neuromuscular synapses in the muscle layer.
The high sensitivity of this marker in very low titers demonstrates all the symptoms of APUD
cells masking vesicles in neuromuscular synapses. This makes it possible to plan treatment based
on important criteria for determining the treatment tactics for various types of esophageal atresia.
