Abstract:
Objective: To determine the level of proinflam mato-
ry and anti-inflammatory cytokines in the blood serum
of patients who underwent anterior colporrhaphy and
posterior colpoperineoplasty levatorplasty. Material and
methods: 90 patients with different stages of pelvic or
gan prolapse according to the POP-Q classification were observed, who were divided into two groups depending
on the use of PRP therapy. Results: During the first week
after surgery, proinflammatory and anti-inflammatory
cytokines were administered to patients in both groups.
After 30 days of the postoperative period, the level of an
ti-inflammatory cytokines was higher in the group where
PRP therapy was performed. Surgical trauma can cause
acute systemic inflammation, which initially plays a role
in immune defense against bacterial infection and in the
wound healing process. Conclusions: When using PRP
therapy, wound healing can be accelerated, and it is also
possible to shorten the rehabilitation period with an im
provement in its course. Keywords: cytokines, inflamma
tion, pelvic organ prolapse, rehabilitation period after
PRP therapy.
