Abstract:
Objective: To study hormonal and biochemical param
eters in women with uterine fibroids after uterine artery
embolization. Material and methods: The studies were
conducted in 2019-2023 in the gynecology department
of the multidisciplinary clinic of the Tashkent Medical
Academy and in the Womens Health Center, in the Central
Research Laboratory, in the Tashkent Dental Institute at
the Department of Biological Chemistry, Biophysics and
Informatics. I l l women were examined, 62 of whom had
symptomatic uterine fibroids. Results: In 40 patients, the
ISSN 2181-7812
main complaint was uterine bleeding of varying intensity
and duration, 24 women complained of lower abdominal
pain, a combination of 2 or more symptoms was noted in
more than 40 patients examined. After surgery, the level of
hormone-binding globulin increases at different times in
the postoperative period, which indicates the activation of
liver function. Conclusions: The enhancement of the liver-
detoxification function on the 6th-8th day after uterine
artery embolization was confirmed by an increase in el
and n-glutathione-S-transferase markers, which indicates
a targeted reduction in myomatous nodes due to the de
velopment of aseptic inflammation.