Abstract:
Liver cirrhosis is a serious disease, being the 11th most frequent cause of death worldwide,
with 50% of patients dying within 5 years. Ascites in cirrhosis develops as a result of various
pathogenetic factors: hyperaldosteronism, fluid accumulation in the body, portal hypertension,
increased lymph production and impaired outflow, reduced drainage function of the parietal
peritoneum, autoimmune dysproteinemia, and disturbance of plasma colloid-oncotic balance. Modern
medicine offers several methods for treating ascites, including drug therapy, serial laparocenteses
with removal of large volumes of fluid, transjugular intrahepatic portosystemic shunts, implanted
drainage devices, as well as acellular and concentrated reinfusion therapy. Each of these approaches
has its advantages and limitations, and choosing the optimal treatment strategy often presents a
challenging task. This article discusses modern methods of ascites treatment using reinfusion with
the Fresenius preparation.
