Abstract:
Purpose of the study. Biochemical
changes in patients with chronic glomerulonephritis and their early detection.
Materials and research methods.
The study involved 104 patients aged 20 to
65 years. All were diagnosed with chron ic glomerulonephritis. The first group (n
= 40) - Anti-Pla2R positive patients with
chronic glomerulonephritis membranous
nephropathy. The second group (n = 11)
- 11 patients with secondary nephropathy due to autoimmune connective tissue
disease. The third group (n = 53) - 53 pa tients with chronic glomerulonephritis
IgA-nephropathy. All patients were recruited from the Republican Specialized
Scientific and Practical Medical Center for
Nephrology and Kidney Transplantation.A
complete urinalysis is important in the
diagnosis of chronic glomerulonephritis.
It reveals varying degrees of proteinuria,
micro- and macrohematuria (redness of
urine or a color similar to “meat wash”),
casts (hyaline, granular, erythrocytic,
waxy) and epithelial cells. In addition to
urine, a complete blood count, biochemical, immunological, UTI, X-ray (to exclude
urological diseases) and morphological
examinations are important in confirming
the diagnosis.
