Abstract:
Localized Scleroderma (LS) is a chronic connective tissue disorder that
predominantly affects the skin and underlying tissues. It is marked by
localized areas of sclerosis accompanied by inflammatory symptoms, such
as erythema and edema, followed by skin atrophy and alterations in
pigmentation (hypo- or hyperpigmentation), as noted by Kubanova in 2010.
While LS can occur at any age, it often develops in a localized form,
presenting with chronic inflammation and fibroatrophic skin and mucosal
lesions. In recent decades, the incidence of LS has increased. Among
children and adolescents, it is the most prevalent form of scleroderma, with
an estimated prevalence of 1 case per 37,000 individuals. Girls are three to
four times more likely than boys to be affected (Kubanova, A.N. Lev., 2013;
Kreuter et al., 2006).
