Abstract:
In recent years, scientists have been paying increasing attention to metabolic syndrome in
women of reproductive age, as it has become one of the most common causes of reproductive
diseases. Population studies show that the prevalence of metabolic syndrome in women is 15-
20%, while in the structure of reproductive system pathologies, metabolic syndrome accounts for
30-35% and is more frequently detected in patients with recurrent hyperplastic processes. The
frequency of endometriosis reaches up to 70%. Numerous studies have demonstrated an
increased risk of developing endometrial, cervical, ovarian, and breast cancer in women with
metabolic syndrome. It has been established that the prevalence of metabolic syndrome (MS) in
women with polycystic ovary syndrome (PCOS) is 43-47%, while the frequency of PCOS in
women with MS is 24%. Notably, almost every woman (91%) with PCOS has some components
of MS, including dyslipidemia (60%), hypertriglyceridemia (35%), obesity (67%), and arterial
hypertension (45%). Most morphological and physiological studies have focused on
morphological changes in the heart and pancreas. However, there are few studies dedicated to
morphological changes in the reproductive organs of women with metabolic syndrome. Taking
this into account, we investigated morphological changes in the uterus and ovaries as the subject
of our research. The obtained results revealed that the main morphological substrate consists of
changes in the form of destruction and defragmentation in the uterus and ovaries.
