Abstract:
The sedative activity of indole flavonoids, including pyrazolone and pyrazolonechloride, during the action of alcohol-induced sleep and fear stimuli was studied using the Sonberg method. In this study, pyrazoline and pyrazoline chloride reduced sleep time by increasing alcohol-induced sleep time, while in the Sonberg method, urine and feces excretion in experimental animals was reduced under the influence of noise and external factors. This suggests that the studied substances have a sedative effect.