Abstract:
Objective: To study the significance of metabolic fatty liver disease and asymptomatic hyperuricemia in osteoarthritis. Material and methods: The study included 70 patients aged 45 to 75 years with a confirmed diagnosis of osteoarthritis of the
knee and hip joints, admitted for treatment to the rheumatology and cardiorheumatology departments of the multidisciplinary
clinic of the Tashkent Medical Academy in 2024. The duration of the disease was on average from 2 to 10 years. Results: Of the
total number of patients, 78.6% suffered from gonarthrosis of the knee joints, 21.4% - arthrosis of the hip joint. The average pain
score on the WOMAC scale was 13.2±1.35, numbness - 4.20±2.26, functional impairment - 43.8±12.3. Conclusions: Osteoarthritis is a leading cause of morbidity, disability and loss of productivity worldwide. Osteoarthritis is associated with a number of
systemic diseases, such as obesity, cardiovascular diseases, type 2 diabetes mellitus, metabolic syndrome.