Abstract:
The article presents data on the results of a comparative study of the clinical and anti-Helicobacter efficacy of two eradication
therapy regimens in 60 patients with Helicobacter Pylori (HP)-associated chronic gastritis. The main group of patients received
eradication therapy consisting of vonoprazan, amoxicillin, clarithromycin, and bismuth tripotassium decitrate for 10 days. The
second group of patients received esomeprazole as an antisecretory drug against the background of similar therapy. It was
shown that in the first group of patients, the dynamics of acid suppression under the influence of vonoprazan was significantly
higher compared to esomeprazole. In the main group of patients, the eradication rate of HP infection was 93%, and in the group
of patients taking esomeprazole, this figure was 80%.
