METABOLIC SYNDROME IN WOMEN WITH VITAMIN D DEFICIENCY: ISSUES OF PATHOGENESIS AND DIAGNOSTICS

Abstract

According to the WHO, 1.7 billion people on the planet are overweight, and by 2025, the number of obese people in the world will reach 300 million people [1]. According to the definition of the World Health Organization, obesity is defined as an unusual or excessive accumulation of fat that can be harmful to health. It is a global medical and social problem for the health of all countries and patients of all ages. The incidence of metabolic syndrome (MS) in the world is almost 40% of the adult population, and obesity is 13% (Lee et al., 2020). The global prevalence of obesity has almost tripled from 1975 to 2016 and continues to increase. In the United States - 42.4% in 2018, in France, the prevalence of obesity among adults was 17% in the same year. Recent studies have shown that both vitamin D deficiency and carriage of certain polymorphisms of the vitamin D receptor gene may be associated with an increase in the fractions of atherogenic blood lipids [2].