Pathomorphological Changes Developing in the Stenosing Variant of Esophageal Atresia in Infants

Abstract

Although the clinical and morphological frequency of atresia, which is the 4th variant of esophageal malformation and continues mainly with esophageal wall stenosis, is relatively low, in most cases patients experience a sudden decrease in quality of life. Morphologically, all anatomical walls of the esophagus of this type contain formed tissue components mainly in those areas that have not undergone stenosis, and in those areas where stenosis is detected, areas that have undergone dysplasia in the esophageal wall are identified. In particular, myodysplasia on the muscular bottoms is characterized by the fact that there are very few alveolar tubular glands on the mucosa and mucous membranes, there are 1-3-layered cuboid and prismatic epithelium on the surface of the mucous membrane, as well as cuboid epithelium cells that undergo metaplasia.