HORMONAL AND BIOCHEMICAL INDICES OF THE LIVER OF WOMEN WITH UTERINE FIBROIDS WITH SURGICAL INTERVENTION

Abstract

Objective: To study hormonal and biochemical param eters in women with uterine fibroids after uterine artery embolization. Material and methods: The studies were conducted in 2019-2023 in the gynecology department of the multidisciplinary clinic of the Tashkent Medical Academy and in the Womens Health Center, in the Central Research Laboratory, in the Tashkent Dental Institute at the Department of Biological Chemistry, Biophysics and Informatics. I l l women were examined, 62 of whom had symptomatic uterine fibroids. Results: In 40 patients, the ISSN 2181-7812 main complaint was uterine bleeding of varying intensity and duration, 24 women complained of lower abdominal pain, a combination of 2 or more symptoms was noted in more than 40 patients examined. After surgery, the level of hormone-binding globulin increases at different times in the postoperative period, which indicates the activation of liver function. Conclusions: The enhancement of the liver- detoxification function on the 6th-8th day after uterine artery embolization was confirmed by an increase in el and n-glutathione-S-transferase markers, which indicates a targeted reduction in myomatous nodes due to the de velopment of aseptic inflammation.