Abstract:
Immunoglobulin A nephropathy (IgA nephropathy) is one of the most common forms of chronic
glomerulonephritis in children and adolescents. The disease is characterized by the deposition of
IgA in the mesangial regions of the glomeruli, leading to the development of an inflammatory
process and impaired renal function. Despite its prevalence, the pathogenesis of the disease remains
incompletely understood, and its clinical course is highly variable — ranging from asymptomatic
hematuria to rapidly progressive renal impairment. Therefore, early diagnosis and optimal therapy
are crucial to prevent progression to chronic kidney failure.
