MEASLES: EPIDEMIOLOGICAL SITUATION, CLINICAL COURSE AND EFFECTIVENESS OF PREVENTIVE MEASURES

Abstract

The aim of this study was to analyze the current epidemiological situation of measles, its clinical course, and the effectiveness of preventive measures. The study was based on epidemiological surveillance of measles cases registered in the Republic of Uzbekistan during 2020–2024. The clinical course was evaluated using data from 120 patients treated in the measles ward of the 3rd Clinic of the Tashkent Medical Academy. The main symptoms of the disease, distribution by age groups, and the relationship with vaccination coverage were analyzed using statistical methods. According to the results, measles was most frequently observed in children aged 1–5 years (68%). The most common clinical signs were fever (95%), rash (100%), cough (85%), and conjunctivitis (70%). The incidence was significantly lower in regions with high vaccination coverage (p<0.05). These findings indicate that measles still remains a pressing health problem. It has been proven that increasing vaccination coverage can reduce the incidence of the disease.