Evaluation of the Morphological Condition of the Pancreas in Alloxan-Induced Diabetic Rats Under Chronic Pesticide Exposure

Abstract

This study explores the effects of chronic pesticide exposure (chlorpyrifos) on the pancreas morphology in rats with experimental diabetes induced by alloxan. The study showed significant histological and morphometric alterations between the control, diabetic, and diabetic + pesticide groups, providing evidence for a synergistic toxic effect of diabetes and pesticide exposure. The results highlight the detrimental impact of environmental toxins, particularly chlorpyrifos, on pancreatic morphology in diabetic conditions