Genetic polymorphism of gene ptpn22 in autoimmune diseases

dc.contributor.author	Rakhimova M.B., Akhmedov Kh.S.
dc.date.accessioned	2024-12-16T19:13:21Z
dc.date.available	2024-12-16T19:13:21Z
dc.date.issued	2024
dc.identifier.citation	Toshkent	en_US
dc.identifier.issn	2181-7812
dc.identifier.uri	http://repo.tma.uz/xmlui/handle/1/367
dc.description.abstract	In this review, we summarize the mechanism of how PTPN22 and its genetic variants are involved in the patho- physiology of autoimmune diseases. In addition, we sum up the findings of studies reporting the genetic association of PTPN22 with different types of diseases, including type 1 diabetes mellitus, systemic lupus erythematosus, juvenile idiopathic arthritis, and several other diseases. By understanding these findings comprehensively, we can explain the complex etiology of autoimmunity and help to determine the criteria of disease diagnosis and prognosis, as well as medication developments.	en_US
dc.language.iso	en	en_US
dc.relation.ispartofseries	UDC;616.72-002.772
dc.subject	PTPN22, single nucleotide polymorphisms, autoimmune diseases, genetic association.	en_US
dc.title	Genetic polymorphism of gene ptpn22 in autoimmune diseases	en_US
dc.type	Article	en_US