GENERAL MORPHOFUNCTIONAL CHARACTERISTICS OF BONE TISSUE REGENERATION UNDER THE INFLUENCE OF EXTREME CLIMATIC FACTORS

Abstract

This article presents an analysis of existing scientific literature on the effects of extreme climatic factors on the process of bone tissue regeneration. The impact of abrupt temperature changes, hypoxia, humidity levels, ultraviolet radiation, and other extreme climatic factors on reparative osteogenesis is discussed. Data reported by various researchers on morphological remodeling of bone tissue, changes in cellular composition, blood supply, and functional characteristics associated with metabolic processes are summarized. In addition, the influence of extreme climatic conditions on osteoblast and osteoclast activity, collagen synthesis, and mineralization processes is analyzed. This literature review contributes to a deeper understanding of the mechanisms of bone regeneration and may serve as a scientific basis for future experimental and clinical studies.