Abstract:
Chronic inflammation contributes to the remodeling of the repiratory tract, resulting in irreversible structural
alterations and a progressive decline in pulmonary function. These pathological changes inevitably compromise the quality
of life in pediatric patients, heightening the risk of early disability and adversely influencing their psychoemotional
well-being. Morever, bronchial obstruction and hypoxic states in individuals with bronchial asthmaprofoundly impact the
regulation of hormonal mechanisms within the reproductive system. Objective. The patient with bronchial asthma with the
hormonal balance features. Materials and methods. 16-year-old patient case report, which is including the anamnesis vitae,
anamnesis morbi, family anamnesis according to the disease, complaints, objective and physical methods of investigation,
laboratory analysis CBT, hormones analysis by CLIA method, instrumental methods to establish the stages of BA. Results
and discussion. Based on patient’s hormonal profile, elevated levels of prolactin and testosterone were identified, suggesting
that stress-induced adaptive mechanisms, along with hormone therapy administered due to the chronic hypoxic state,
inevitably influenced the pituitary function within endocrine system. Conclusion. Sex hormones play a crucial role in
pathogenesis and progressin of bronchial asthma. Estrogens contribute to heightened bronchial hyperreactivity, whereas
testosterone, in contrast, exhibits protective effects
