KLOTHO PROTEIN AND VITAMIN D AS NOVEL BIOMARKERS  FOR EARLY RENAL DYSFUNCTION IN HYPERTENSIVE  PATIENTS: DIAGNOSTIC VALUE AND THERAPEUTIC  IMPLICATIONS

dc.contributor.author	Saidov K. Sh., Rahimova M.E.
dc.date.accessioned	2026-06-12T04:36:35Z
dc.date.available	2026-06-12T04:36:35Z
dc.date.issued	2026-05-14
dc.identifier.uri	http://repo.tma.uz/xmlui/handle/1/4322
dc.description.abstract	This study investigated the diagnostic value of Klotho protein and vitamin D in the early detection of renal dysfunction in patients with hypertension. Serum levels of cystatin-C, Klotho protein, vitamin D, and parathyroid hormone were evaluated in 169 hypertensive patients and 23 healthy volunteers. Correlations between these biomarkers across different stages of hypertension were established. The addition of vitamin D supplementation (Detrimax 5000 IU) to standard therapy demonstrated a statistically significant positive effect on hemodynamic parameters and markers of renal dysfunction.	en_US
dc.language.iso	en_US	en_US
dc.publisher	Spain (Global Conference on Medical and Health Sciences)	en_US
dc.subject	Hypertension, renal dysfunction, Klotho protein, vitamin D, cystatin C, early diagnosis, nephroprotection.	en_US
dc.title	KLOTHO PROTEIN AND VITAMIN D AS NOVEL BIOMARKERS FOR EARLY RENAL DYSFUNCTION IN HYPERTENSIVE PATIENTS: DIAGNOSTIC VALUE AND THERAPEUTIC IMPLICATIONS	en_US
dc.type	Article	en_US