CONDITION OF DYSLIPIDEMIA AND CYTOKINE PROFILE IN PATIENTS WITH  GOUT: THE ROLE OF IL-6, IL-18 AND THE PLACE OF HYPERURICEMIA IN THE  DEVELOPMENT OF METABOLIC DISORDERS

Nabieva D.A.1, Khidoyatova M.R.2, Agzamova G.S.3, Abduazizova N.X.4, Matchanov S.X.5,  Midasov M.M.6, Shiranova Sh.A.7

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dc.contributor.author	Nabieva D.A.1, Khidoyatova M.R.2, Agzamova G.S.3, Abduazizova N.X.4, Matchanov S.X.5, Midasov M.M.6, Shiranova Sh.A.7
dc.date.accessioned	2026-07-09T18:46:28Z
dc.date.available	2026-07-09T18:46:28Z
dc.date.issued	2023-07
dc.identifier.uri	http://repo.tma.uz/xmlui/handle/1/4782
dc.description.abstract	Objective: to investigate the relationship between indexes of dyslipidemia and immunological changes in patients with tophaceous gout and asymptomatic hyperuricemia. Patients and methods. The study included 85 male patients: 1st group – 49 patients with primary chronic gout according to Wallace S.L. criteria, 2nd (control) group – 36 patients with asymptomatic hyperuricemia. The levels of uric acid (UA), C-reactive protein (CRP), fasting glycemia, lipid profile – total cholesterol (TC), triglycerides (TG), high-density (HDL), low density (LDL), very low density (VLDL) lipoproteins, atherogenic ratio (AR); cytokine concentrations: interleukin-1β (IL 1β), tumor necrosis factor-α (TNF-α), IL-4, IL-6, IL-8, IL-10 and IL-18 in the blood serum using enzyme-linked immunosorbent assay.	en_US
dc.language.iso	en_US	en_US
dc.publisher	Journal of Hunan University（Natural Sciences）Vol. 50. No. 07.	en_US
dc.subject	gout; hyperuricemia; dyslipidemia; interleukins; cytokine profile.	en_US
dc.title	CONDITION OF DYSLIPIDEMIA AND CYTOKINE PROFILE IN PATIENTS WITH GOUT: THE ROLE OF IL-6, IL-18 AND THE PLACE OF HYPERURICEMIA IN THE DEVELOPMENT OF METABOLIC DISORDERS	en_US
dc.type	Article	en_US