Dynamics of Ferrokinetics Parameters in Patients With Rheumatoid Arthritis Associated With Helicobacter Pylori Infection on the Background of Complex Treatment Including Iron Preparations

Abstract

Abstract: Despite certain advances in understanding the pathogenesis and developing new therapeutic approaches for rheumatoid arthritis (RA), achieving stabilization of its clinical course remains challenging. The presence of comorbid conditions such as anemia and gastroduodenal involvement poses a significant risk to patients' lives and entails substantial financial costs for the treatment and prevention of RA. Modern rheumatology pays special attention to the early detection of diseases. Currently, there is evidence that the preclinical period of systemic autoimmune reaction is associated with dysregulation of immune interactions with synanthropic microflora. This article discusses the disturbances in ferrokinetics in patients with rheumatoid arthritis associated with iron- deficiency anemia and H. pylori, as well as the results of correcting the anemic syndrome with iron preparations.