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COMPARATIVE ANALYSIS OF FOLATE CYCLE MARKERS IN PATIENTS WITH TYPE 2 DIABETES COMPLICATED BY DIABETIC NEPHROPATHY

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dc.contributor.author Barno Kh. Shagazatova 1, Said K. Bakhadirov 2, Bakhtiyor R. Mamasodikov 3
dc.date.accessioned 2024-11-20T10:08:00Z
dc.date.available 2024-11-20T10:08:00Z
dc.date.issued 2024
dc.identifier.uri http://repo.tma.uz/xmlui/handle/1/89
dc.description.abstract One of the most studied genetic factors in the context of DN is the methylenetetrahydrofolate reductase (MTHFR) gene, specifically the C677T polymorphism. This single nucleotide polymorphism (SNP) is associated with elevated plasma homocysteine levels, which are known to contribute to vascular damage and the progression of nephropathy in diabetic patients. Research consistently shows that the 677T allele, particularly in individuals with the homozygous form (TT genotype), significantly increases the risk of developing DN across various populations. en_US
dc.language.iso en_US en_US
dc.publisher Central Asian Journal of Medicine en_US
dc.subject mitral valve genetic polymorphisms, diabetic nephropathy, markers. en_US
dc.title COMPARATIVE ANALYSIS OF FOLATE CYCLE MARKERS IN PATIENTS WITH TYPE 2 DIABETES COMPLICATED BY DIABETIC NEPHROPATHY en_US
dc.type Article en_US


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