PATHOLOGOANATOMICAL FEATURES OF CHILDHOOD LEUKEMIAS:  MORPHOLOGY OF ACUTE LYMPHOBLASTIC LEUKEMIA

dc.contributor.author	Sardor U. Zubtiyev., Shakhboz H. Abdulloyev., Gulkhayyo B. Orifova
dc.date.accessioned	2026-05-16T12:56:06Z
dc.date.available	2026-05-16T12:56:06Z
dc.date.issued	2026.05.16
dc.identifier.uri	http://repo.tma.uz/xmlui/handle/1/4031
dc.description.abstract	Acute lymphoblastic leukemia (ALL) in children is one of the most common malignant disorders of the hematopoietic system. This study investigates the pathologoanatomical and morphological features of ALL. Findings revealed diffuse infiltration of blast cells in the bone marrow, lymph nodes, spleen, liver, and thymus. Histological analysis demonstrated high proliferative activity of blasts and suppression of normal hematopoiesis. Immunohistochemical results confirmed the expression of CD10, CD19, and TdT markers in B-ALL, while CD3 was characteristic for T-ALL. The obtained data indicate the systemic nature of organ involvement in ALL and highlight the importance of morphological examination in early diagnosis.	en_US
dc.language.iso	en_US	en_US
dc.publisher	O'zbekiston (Central Asian Journal of Medicine) № 4	en_US
dc.relation.ispartofseries	UDC;616.155.392-053.2:611-018
dc.subject	acute lymphoblastic leukemia; children; pathomorphology; bone marrow; blast cells; immunohistochemistry; thymus.	en_US
dc.title	PATHOLOGOANATOMICAL FEATURES OF CHILDHOOD LEUKEMIAS: MORPHOLOGY OF ACUTE LYMPHOBLASTIC LEUKEMIA	en_US
dc.type	Article	en_US