PATHOGENETIC MECHANISMS LINKING GASTROESOPHAGEAL REFLUX DISEASE WITH RESPIRATORY DISEASES

dc.contributor.author	Raimkulova N.R., Subkhanova Z.S
dc.date.accessioned	2026-06-20T16:13:10Z
dc.date.available	2026-06-20T16:13:10Z
dc.date.issued	2024
dc.identifier.uri	http://repo.tma.uz/xmlui/handle/1/4510
dc.description.abstract	To study the pathogenetic mechanisms and clinical manifestations of GERD in asthma and COPD. Methods: A study of 68 patients with GERD, asthma, and COPD; diagnostics included impedance-pH monitoring, spirometry, and analysis of inflammatory markers (CRP, IL-6, IL-8). Results: Aspiration was more frequent in COPD (60%) and asthma (42%) patients. Elevated CRP, IL-6, IL-8 levels and vagal reflex hyperactivity were associated with bronchospasms. Conclusions: GERD exacerbates respiratory symptoms, requiring a comprehensive treatment approach.	en_US
dc.language.iso	en_US	en_US
dc.publisher	O'zbekiston, Toshkent (YEVROSIYO PEDIATRIYA AXBOROTNOMASI) TIBBIY ILMIY- INNOVATSION JURNAL №2(20)	en_US
dc.subject	GERD, asthma, COPD, pathogenetic mechanisms, aspiration, vagal reflex, inflammation, impedance-pH monitoring.	en_US
dc.title	PATHOGENETIC MECHANISMS LINKING GASTROESOPHAGEAL REFLUX DISEASE WITH RESPIRATORY DISEASES	en_US
dc.type	Article	en_US