Tashkent Medical Academy Repository: Recent submissions

  • FEATURES OF HEMATOLOGICAL MANIFESTATIONS IN RHEUMATOID ARTHRITIS 
    Karimov M.Sh., Eshmurzaeva A.A., Sibirkina M.V., Marufhanov H.M. (2021-10-09)
    Цель. Выявить лабораторные особенности проявления анемического синдрома у больных с суставной и висцеральной формами ревматоидного артрита. Материал и методы. Клиническим материалом для исследования послужили 54 ...
  • МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКИЕ МЕХАНИЗМЫ ФОРМИРОВАНИЯ РЕВМАТОИДНОГО АРТРИТА 
    Каримов М.Ш., Эшмурзаева А.А. (2021-04-16)
    Важную медицинскую и социально значимую проблему современной ревматологии представляет ревматоидный артрит (РА), являющийся весьма сложным заболеванием с до конца не определенными этиологическими факторами и патогенетическими ...
  • ВОПРОСЫ ПАТОГЕНЕЗА РЕВМАТОИДНОГО АРТРИТА 
    Каримов М.Ш., Эшмурзаева А.А., Азимова М.М., Сибиркина М.М. (2021-06-05)
    Revmatoid artritga olib keladigan jarayonlarning shakllanishining patogenetik mexanizmlarini o’rganishda sezilarli yutuqlarga qaramay, kasallikning sababchi omillari va mexanizmlari to’liq tushunilmagan. Shu bilan ...
  • ИЗУЧЕНИЕ ПОЛИМОРФИЗМА ГЕНОВ ФОЛАТНОГО ЦИКЛА У ПАЦИЕНТОВ С РЕВМАТОИДНЫМ АРТРИТОМ 
    А.А. Эшмурзаева, Каримов М.Ш. (2021-02-11)
    Нами изучена ассоциация полиморфизма MTRR (rs1801394) с риском развития ревматоидного артрита среди населения Узбекистана. Оценку данного генетического полиморфизма осуществляли с помощью анализа образцов ДНК ...
  • РОЛЬ ИММУНОГЕНЕТИЧЕСКИХ МАРКЁРОВ В РАЗВИТИИ РЕВМАТОИДНОГО АРТРИТА 
    Каримов М.Ш., Эшмурзаева А.А., Сибиркина М.В. (2021-04-09)
    В ходе проведенных исследований было выявлено, что аллель G и гетерозиготный генотип А/G гена IL17F (rs763780) среди пациентов с РА встречаются существенно выше по сравнению с контрольной группой. В частности, наиболее ...
  • THE ROLE OF GENETIC POLYMORPHISM OF THE IL23R GENE RECEPTOR (11209026) IN THE MECHANISMS OF DEVELOPMENT OF RHEUMATOID ARTHRITIS IN UZBEKISTAN 
    Marif Sh. Karimov Tashkent Medical Academy, Tashkent, 100109, Uzbekistan, m.sh.karimov@mail.ru Aida A. Eshmurzaeva Tashkent Medical Academy, Tashkent, 100109, Uzbekistan, aida474@mail.ru Asiya R. Gimadutdinova Tashkent Medical Academy, Tashkent, 100109, Uzbekistan, asiya555@mail.ru (2021-04-11)
    The presence of a relationship between polymorphism of the IL23R gene receptor (11209026) and the risk of developing rheumatoid arthritis in Uzbekistan was studied. The polymorphism of the IL23R gene receptor (11209026) ...
  • FEATURES OF THE PREVALENCE OF RHEUMATOID ARTHRITIS (LITERATURE REVIEW) 
    Marif Sh. Karimov Tashkent Medical Academy, Tashkent, 100109, Uzbekistan, m.sh.karimov@mail.ru Aida A. Eshmurzaeva Tashkent Medical Academy, Tashkent, 100109, Uzbekistan, aida474@mail.ru Khamid M. Marufhanov Tashkent Medical Academy, Tashkent, 100109, Uzbekistan, x.m.marufhanov@mail.ru (2021-04-11)
    According to the results of modern research, it is obvious that rheumatoid arthritis is widespread among the world population. The polymorphism and severity of clinical manifestations, with a high incidence of extra-articular ...
  • Association of Rs763780 Polymorphism of Gene IL17F with the Risk of Developing Rheumatoid Arthritis in Uzbekistan 
    M. Sh. Karimov, A. A. Eshmurzaeva, Kh. M. Marufkhanov & M. V. Sibirkina (2021-11-27)
    As a result of the study conducted, it was witnessed that the G allele and the heterozygous A / G genotype of the IL17F gene (rs763780) among patients with RA are significantly higher than in the control group. In ...
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  • The Incidence of Anemia in Patients with Rheumatoid Arthritis 
    Aida Eshmurzaeva1, Marif Karimov1, Iskandar Mavlyanov1, Marina Sibirkina1, Nigora Tukhtaeva1 and Bekhzod Abdullaev2 (2016-07-01)
    Rheumatoid arthritis (RA) is an autoimmune, systemic disease that affects the joints. In RA, the body’s immune system destroy body’s tissue for a foreign invader. This leads immune system to attack the protective cushion ...
  • ENDOGENOUS PATHOLOGICAL FACTORS AS THE REASON OF SYSTEM INFLAMMATORY REACTION DURING RHEUMATOID ARTHRITIS 
    Aida Eshmurzaeva1, Ma’rif Karimov2, Iskandar Mavlyanov3, Abdug’ofir Khadzhimetov4, Mariya Sibirkina5, Bekhzod Abdullaev6* (2016-02-16)
    Rheumatoid arthritis (RA) is an autoimmune, systemic disease that affects the joints. In RA, the body‟s immune system destroy body‟s tissue for a foreign invader. This leads immune system to attack the protective cushion ...
  • THE VALUE OF ENDOTHELIAL DYSFUNCTION IN THE GENESIS OF DEVELOPMENT RHEUMATOID ARTHRITIS 
    Aida A. Eshmurzaeva, Abdug’ofir Khodjimetov and 2Bekhzod Abdullaev (2016-05-16)
    Rheumatoid arthritis (RA) is an autoimmune, systemic disease that affects the joints. In RA, the body’s immune system destroy body’s tissue for a foreign invader. This leads immune system to attack the protective cushion ...
  • SYNDROME OF INCREASED EPITHELIAL PERMEABILITY IN PATIENTS WITH RHEUMATOID ARTHRITIS 
    Marufhanov H.M., Sibirkina M.V., Eshmurzayeva A. A. (2023-02-27)
    Currently, the role of the syndrome of increased epithelial permeability of the mucous membrane of the gastrointestinal tract, primarily the intestine, as the main pathogenetic mechanism for the development of inflammatory ...
  • Ferrokinetics in Patients with Rheumatoid Arthritis 
    Eshmurzaeva A.A. Tashkent Medical Academy Sibirkina M.V. Tashkent Medical Academy (2023-06-01)
    heumatoid arthritis (RA) is an inflammatory disease of the joints, the main symptom of which is the development of symmetrical synovitis with a tendency to destructive changes in the joints, which affects an average of ...
  • СОСТОЯНИЕ ФЕРРОКИНЕТИКИ У БОЛЬНЫХ РА С АНЕМИЕЙ И НАЛИЧИЕМ ХЕЛИКОБАКТЕРНОЙ ИНФЕКЦИИ НА ФОНЕ КОМПЛЕКСНОГО ЛЕЧЕНИЯ С ВКЛЮЧЕНИЕМ ФЕРРОПРЕПАРАТА. 
    Эшмурзаева А.А., Сибиркина М.В. (2023-07-01)
    В исследование было включено 70 пациентов с достоверным РА, находившихся на стационарном лечении в ревматологическом отделении 3 клиники ТМА. Все больные разделены на 2 группы.1-ая группа больные РА с анемией (38) и ...
  • Studying the Association of MTRR (rs1801394) Genetic Polymorphism with the risk of Developing Rheumatoid Arthritis in Uzbekistan 
    Marif Sh. Karimov Karimov Marif Shakirovich – Doctor of Medical Sciences, Professor, Head of the department of propaedeutics internal diseases, Tashkent medical academy; Aida A. Eshmurzayeva Eshmurzayeva Aida Abduganiyevna. - DSc, Associate Professor of the department of propaedeutics internal diseases, Tashkent medical academy Fazilat N. Shukurova Shukurova Fazilat Narmamatovna – PhD, associate professor of the department of propaedeutics internal diseases, Tashkent medical academy, Tashkent, Uzbekistan Email: fazilatshukurova@gmail.com +998973330686 Marina V. Sibirkina Sibirkina Marina Valerovna - PhD, associate professor of the department of propaedeutics internal diseases, Tashkent medical academy; Asiya R. Gimadutdinova Gimadutdinova Asiya Rinatovna - assistant of the department of propaedeutics internal diseases, Tashkent medical academy; (2023-06-16)
    We have studied the association of MTRR polymorphism (rs1801394) with the risk of developing rheumatoid arthritis among the population of Uzbekistan. The assessment of this genetic polymorphism was carried out by analyzing ...
  • Microbiocenosis of the Gastrointestinal Tract in Rheumatological Patients Taking NSAIDs 
    Marufkhanov Khamid Makhmudovich Doctor of Medical Sciences, Associate Professor of the Department of Propaedeutics of Internal Diseases No. 2, Tashkent Medical Academy, Tashkent, Uzbekistan Sibirkina Marina Valerievna Candidate of Medical Sciences, Associate Professor of the Department of Propaedeutics of Internal Diseases No. 2, Tashkent Medical Academy, Tashkent, Uzbekistan Eshmurzaeva Aida Abduganiyevna Candidate of Medical Sciences, Associate Professor of the Department of Propaedeutics of Internal Diseases No. 2, Tashkent Medical Academy, Tashkent, Uzbekistan Nurmetov Khabibullo Tulkinovich Candidate of Medical Sciences, Senior Lecturer of the Department of Propaedeutics of Internal Diseases No. 2, Tashkent Medical Academy, Tashkent, Uzbekistan (2023-03-01)
    Modern rheumatology pays special attention to the detection of diseases at the earliest possible stages. To date, there is evidence that the preclinical period of a systemic autoimmune reaction is associated with ...
  • ОСОБЕННОСТИ КЛИНИКО-ГЕМАТОЛОГИЧЕСКИХ ПРОЯВЛЕНИЙ ПРИ РЕВМАТОИДНОМ АРТРИТЕ 
    Эшмурзаева А.А., Сибиркина М.В. (2023-05-05)
    Ревматоидный артрит (РА) - воспалительное заболевание суставов, основным признаком которого является развитие симметричного синовита со склонностью к деструктивным изменениям в суставах, которое поражает в среднем 1-2% ...
  • ЗНАЧЕНИЕ ГЕПСИДИНА В ПАТОГЕНЕЗЕ АНЕМИИ У БОЛЬНЫХ РЕВМАТОИДНЫМ АРТРИТОМ 
    Эшмурзаева А.А (2023-01-01)
    Анемия при ревматоидном артрите является типичным примером анемии при хронических заболеваниях. Основной механизм развития анемии – это нарушение утилизации железа костным мозгом в результате действия гепсидина, экспрессия ...
  • Parameters of Apoptosis and Proliferative Activity in the Stomach in Patients with Rheumatological Diseases 
    Marufkhanov Khamid Makhmudovich, Sibirkina Marina Valerievna,Eshmurzaeva Aida Abduganiyevna (2023-06-11)
    Programmed cell death (PCD) is one of the key links in the pathogenesis of gastritis and peptic ulcer disease. In the course of the study, the proliferative-apoptotic status of epithelial cells of the gastric mucosa was ...